Table 1.
Clinical characteristics of the study patients depending on the cut-off obtained for AKI prediction.
| <178 μg/L | ≥178 μg/L | p value | |
|---|---|---|---|
| n | 55 | 45 | — |
| Age (years) | 54.9 ± 18.5 | 64 ± 15.5 | 0.009 |
| Male | 37 (67) | 23 (51) | 0.075 |
|
| |||
| Characteristics at ICU admission | |||
| SAPS II | 37.8 ± 14.3 | 43.15 ± 15.5 | 0.095 |
| APACHE II | 15 ± 6.9 | 18 ± 8.2 | 0.059 |
| SOFA | 5.2 ± 2.7 | 7.7 ± 3.6 | <0.0001 |
| AKI admission (%) | 6 (10.9) | 27 (15.6) | <0.0001 |
| KDIGO stage 3 at admission (%) | 2 (3.6) | 12 (26.7) | 0.001 |
| RRT admission (%) | 2 (3.6) | 3 (6.7) | 0.400 |
| Creatinine clearance (mL/min) | 109 ± 58 | 57 ± 52 | <0.0001 |
| Cockcroft–Gault | 104 ± 47 | 58 ± 38 | <0.0001 |
|
| |||
| Characteristics during ICU stay | |||
| Mechanical ventilation (%) | 46 (82) | 36 (80) | 0.410 |
| Vasopressor requirement (%) | 6 (11) | 22 (49) | <0.0001 |
| ICU length of stay (days) | 11.1 ± 9.3 | 9.4 ± 10 | 0.360 |
| ICU mortality (%) | 10 (18.2) | 12 (26.7) | 0.210 |
| Sepsis | 3 (5.5) | 26 (57.8) | 0.007 |
| Septic shock | 2 (3.6) | 18 (40) | <0.0001 |
| AKI development (%) | 2 (3.6) | 6 (13.3) | 0.070 |
| KDIGO stage 3 development (%) | 2 (3.6) | 16 (35.6) | <0.0001 |
| RRT after admission (%) | 0 (0) | 4 (8.9) | 0.038 |
| RRT total (%) | 2 (3.6) | 7 (15.6) | 0.040 |
Values expressed as either % per column or mean ± standard deviation. p: value of statistical significance. SAPS II: Simplified Acute Physiology Score II; APACHE II: Acute Physiology and Chronic Health Evaluation II; SOFA: Sequential Organ Failure Assessment score; AKI: acute kidney injury; KDIGO: Improving Global Outcomes AKI group classification; RRT: Renal replacement therapies; ICU: intensive care unit.