Table 2.
SNP | Gene | Position | Alleles | MAF | p a value | ORs | 95% CI | p b value | ||
---|---|---|---|---|---|---|---|---|---|---|
A/B | case | control | for HWE | |||||||
rs243866 | MMP2 | 16q12.2 | A/G | 0.112 | 0.173 | 0.329 | 0.79 | 0.56 | 1.13 | 0.194 |
rs243864 | MMP2 | 16q12.2 | G/T | 0.112 | 0.140 | 0.342 | 0.78 | 0.55 | 1.10 | 0.151 |
rs865094 | MMP2 | 16q12.2 | G/A | 0.290 | 0.266 | 1.000 | 1.13 | 0.87 | 1.45 | 0.357 |
rs11646643 | MMP2 | 16q12.2 | G/A | 0.175 | 0.205 | 0.601 | 0.83 | 0.62 | 1.11 | 0.202 |
rs2241146 | MMP2 | 16q12.2 | A/G | 0.234 | 0.213 | 0.611 | 1.13 | 0.86 | 1.48 | 0.388 |
rs9928731 | MMP2 | 16q12.2 | T/C | 0.486 | 0.476 | 0.170 | 1.04 | 0.83 | 1.31 | 0.719 |
rs470154 | MMP10 | 11q22.2 | T/G | 0.149 | 0.107 | 1.000 | 1.45 | 1.03 | 2.05 | 0.032∗ |
rs17293607 | MMP10 | 11q22.2 | G/A | 0.003 | 0.005 | 1.000 | 0.72 | 0.12 | 4.32 | 0.931 |
SNP: single nucleotide polymorphism, HWE: Hardy-Weinberg equilibrium, OR: odds ratio, 95% CI: 95% confidence interval, and MAF: minor allele frequency.
a P values were calculated by exact test.
b P values were calculated by Pearson Chi-squared test.