Table 2.
Comparison of subgroups distinguished according to the modified Rankin scale at discharge.
| Modified Rankin scale at discharge | ||||
|---|---|---|---|---|
| 0-1 (no significant disability) (N = 85) | 2-3 (mild/moderate disability) (N = 68) | 4-5 (moderately severe and severe disability) (N = 63) | 6 (death) (N = 24) | |
| Age (years) | 67 ± 11 | 71 ± 10 | 76 ± 11^^^ | 79 ± 11^^^ |
| Gender (men/women) | 48/37 | 33/35 | 18/45 | 10/14 |
| History of previous stroke (n/%) | 14 (16.5) | 14 (20.6) | 10 (15.9) | 4 (16.7) |
| Concomitant diseases | ||||
| Hypertension (n/%) | 71 (83.5) | 60 (88.2) | 54 (85.7) | 18 (75.0) |
| Coronary artery disease (n/%) | 26 (30.6) | 15 (22.1) | 20 (31.8) | 8 (33.3) |
| Valvular diseases (n/%) | 7 (8.2) | 7 (10.3) | 9 (14.3) | 1 (4.2) |
| Atrial fibrillation (n/%) | 17 (20.0) | 15 (22.1) | 27 (42.9)^^ | 11 (45.8)^ |
| Obesity (n/%) | 18 (21.2) | 8 (12.8) | 16 (25.4) | 2 (8.3) |
| Diabetes (n/%) | 25 (29.4) | 22 (32.3) | 26 (41.3) | 11 (45.8) |
| Hypercholesterolemia (n/%) | 37 (43.5) | 35 (51.5) | 29 (46.0) | 6 (25.0) |
| Statin therapy (n/%) | 36 (42.3) | 26 (38.2) | 22 (34.9) | 8 (33.3) |
| Active smokers (n/%) | 20 (23.5) | 13 (19.1) | 11 (17.5) | 1 (4.2) |
| Estimated glomerular filtration rate (eGFR) (mL/min/1. 73 m2) | 72.9 ± 23.4 | 74.4 ± 29.2 | 64.1 ± 21.3 | 67.1 ± 26.0 |
| eGFR < 60 mL/min/1. 73 m2 (n/%) | 20 (23.5) | 22 (32.3) | 32 (50.8)^^^ | 12 (50.0)^ |
| C-reactive protein (CRP) (mg/L) | 3.8 (1.3–9.3) | 4.3 (2.6–9.1) | 4.2 (1.7–10.6) | 4.3 (8.5–8.5) |
| Calcium (mg/dL) | 2.35 ± 0.22 | 2.31 ± 0.21 | 2.31 ± 0.18 | 2.28 ± 0.17 |
| Phosphorus (mg/dL) | 1.13 (0.98–1.31) | 1.16 (0.94–1.43) | 1.11 (0.96–1.32) | 1.05 (0.98–1.24) |
| Intact parathyroid hormone (iPTH) (pg/mL) | 36.5 (21.7–49.8) | 37.2 (24.9–57.1) | 46.9 (31.1–66.9)^ | 47.4 (35.2–60.7) |
| iPTH > 65 pg/mL (n/%) | 10 (11.8) | 15 (22.1) | 17 (27.0) | 6 (25.0) |
| Intact fibroblast growth factor 23 (iFGF23) (pg/mL) | 42.3 (10.6–77.2) | 58.7 (17.8–92.4) | 51.5 (25.3–92.2) | 48.2 (19.9–102.1) |
| iFGF23 > 50 pg/mL (n/%) | 37 (43.5) | 39 (57.4) | 33 (52.4) | 11 (45.8) |
| 25-OH-D (ng/mL) | 9.6 (4.8–14.7) | 8.4 (4.9–13.4) | 7.2 (3.0–12.1) | 6.3 (3.4–9.8) |
| 25 − OH − D < 10 ng/mL (n/%) | 48 (56.5) | 43 (63.2) | 42 (66.7) | 18 (75.0)^ |
| One-year survival N (%) | 80 (94.1) | 58 (85.3) | 45 (71.4)^^^ | — |
| Two-year survival N (%) | 60 (91.7) | 40 (82.1) | 27 (57.8)^^^ | — |
^ p < 0.05; ^^p < 0.01; ^^^p < 0.001 vs. minor stroke (0-1).