Table 2.
Postoperative adverse events (as graded by CTCAE severity score v 5.0).
| Adverse events | N | % | Grade 1/2 | Grade 3 | Grade 4 | Grade 5 |
|---|---|---|---|---|---|---|
| HIPEC-related | 9 | 10.2 | 9 | — | — | — |
| Renal | 6 | 6 | — | — | — | |
| Hematological | 3 | 3 | — | — | — | |
| Infectious complications | 42 | 47.7 | 31 | 7 | 1 | 3 |
| Sepsis | 2 | — | — | — | 2 | |
| Abdominal abscess | 8 | — | 7 | — | 1 | |
| Central line-associated bloodstream infections | 11 | 11 | — | — | — | |
| Wound infection | 15 | 15 | — | — | — | |
| Pneumonia | 6 | 5 | — | 1 | — | |
| Noninfectious complications | 37 | 42.1 | 11 | 11 | 11 | 4 |
| Acute postoperative pancreatitis | 4 | — | 3 | 1 | — | |
| Pleural effusion | 10 | 7 | 3 | — | — | |
| Deep vein thrombosis | 2 | 2 | — | — | — | |
| Transient ischemic attack | 1 | — | — | 1 | — | |
| Pulmonary embolism | 2 | — | — | — | 2 | |
| Respiratory failure | 4 | 2 | — | 2 | — | |
| Bowel perforation | 4 | — | — | 3 | 1 | |
| Anastomotic dehiscence | 1 | — | — | 1 | — | |
| Colostomy necrosis | 1 | — | — | 1 | — | |
| Urinary fistula | 2 | — | 2 | — | — | |
| Peritoneal bleeding | 2 | — | 2 | — | — | |
| Gastric bleeding | 1 | — | 1 | — | — | |
| Acute myocardial infarction | 3 | — | — | 2 | 1 | |
| Total | 88 | 51 (57.9%) | 18 (20.4%) | 12 (13.6%) | 7 (0.8%) |