Figure 5.
Effect of DBB and HIS on the changes in serum biochemical factors caused by SOR.
Notes: (A–I) Changes in serum biochemical factors from before to after SOR administration were compared between the groups treated with or without DBB or HIS. The values represent means ± SD (n=6 for each group). N.S., not significant, Kruskal–Wallis test followed by Dunn’s multiple comparison tests.
Abbreviations: AST, aspartate aminotransferase; ALT, alanine aminotransferase; TBIL, total bilirubin; TC, total cholesterol; TG, triglycerides; PT, prothrombin time; BUN, blood urea nitrogen; CRE, creatinine; PLT, platelets; SOR, sorafenib; DBB, dried bonito broth; HIS, histidine
