Table 1.
Human chimerism | Transduction rates in human cells | Transduction rates in total WBCs | |
---|---|---|---|
Mix | Reference | Reference | Reference |
3× | − | ± | − |
SCF | − | − | − |
No prestimulation | + | − | ± |
4 h prestimulation | ± ~ + | ± ~ − | ± |
+ IL-3 | ± | ± | ± |
10% FBS | ± | − | ± |
Abbreviations: FBS, fetal bovine serum; HSC, hematopoietic stem cell; IL, interleukin; SCF, stem cell factor; WBCs, white blood cells; +, increase; −, decrease; ±, no change.