Fig. 7.

HS suppresses HI-induced synapse deficits linked to regulating complement expression in the lesioned cortex. a Double staining PSD95 (red) and C1q (Green) within the ipsilateral cortex were examined at 3 days post-HI. C1q labeled cells (green) were detected in the infract core and lesion boundary zone (IBZ). Scale bar = 500 μm. b Magnified views of boxed regions in A showing PSD95 and C1q staining. Scale bar = 50 μm. c Magnified views of boxed regions in b showing PSD95 and C1q staining. Yellow arrows showing PSD95 and C1q co-location. Red arrows showing C1q-positive cells and PSD95-negative cells. Scale bar = 20 μm. N = 4/group. Values represent the mean ± SD, **p < 0.01, ***p < 0.001 according to ANOVA