Figure 3.

Detection of psoriasis serum proteins using DIA-MS. (A) High throughput screening of serum from psoriasis patients using DIA-MS; (B and C) Reproducibility of DIA-MS detection of serum proteins; (D) Identification of psoriasis-associated proteins in serum using volcano plot analysis; (E) Box plot analysis of newly identified serological psoriasis-associated proteins in inflammation and blood coagulation pathways. The selection of differentially expressed proteins was performed using the Satterthwaite t-test analysis (p-value = 0.05). N and P represent healthy controls and psoriatic patients, respectively. *, ** and *** represent the p-value less than 0.05, 0.005 and 0.0005, respectively.