Table S2.
Risk of exacerbations and mortality according to the stage of diagnosis (early versus late): patients excluding those with concomitant asthma (COPD-only population)
| Years since index date | Risk of exacerbation, percentage of patients without event (95% CI) | Risk of mortality, percentage of patients without event (95% CI) | ||
|---|---|---|---|---|
| Early diagnosis | Late diagnosis | Early diagnosis | Late diagnosis | |
| 2.5 | 35.9 (34.3–37.6) | 19.0 (17.9–20.2) | 81.6 (80.1–82.9) | 80.2 (79.0–81.4) |
| 5.0 | 24.0 (22.4–25.5) | 12.0 (11.0–13.1) | 68.6 (66.9–70.3) | 65.3 (63.7–66.9) |
| 7.5 | 17.4 (15.9–18.9) | 8.3 (7.3–9.4) | 56.1 (54.0–58.1) | 53.9 (51.9–55.8) |
| 10.0 | 14.2 (12.8– 15.6) | 6.3 (5.3–7.4) | 45.6 (43.3–47.8) | 42.9 (40.5–45.3) |
| 12.5 | 12.8 (11.4–14.3) | 5.4 (4.4–6.6) | 36.3 (33.7–38.9) | 34.5 (31.6–37.5) |
| 15.0 | 11.7 (10.1–13.3) | 4.8 (3.6–6.2) | 29.7 (26.4–33.1) | 24.3 (20.0–28.9) |
| 17.5 | 11.7 (10.1–13.3) | 4.8 (3.6–6.2) | 24.7 (19.6–30.1) | 20.6 (13.5–28.8) |
Abbreviations: CI, confidence interval; COPD, chronic obstructive pulmonary disease.