Table 3b.
The clinical evidence of Nigella sativa and its constituents effects on various respiratory diseases
| Plant preparations | Dose /route of administration/treatment period | Study models | Effects | Reference | |
|---|---|---|---|---|---|
| Clinical evidence | Boiled aqueous extract | 18.7mg/kg/day of 50g%) (administered orally for 2 months) |
Chemical war victims | Decreased the use of inhaler and oral β-agonists and oral corticosteroid in the study group Improved PFT values, respiratory symptoms and chest wheeze |
(Boskabady and Farhadi, 2008 ▶) |
| N. sativa oil | 1.808µg/kg/day (administered nasally for 2 weeks) |
Patients with nasal dryness | Improved nasal dryness, obstruction and crusting No effect on mucociliary clearance, nasal burning and itching |
(Oysu et al., 2014 ▶) | |
| N. sativa seed powder | 14.4mg/kg/day (administered orally for 7 days) |
Tonsillo-pharyngitis patients | Improved clinical symptoms | (Dirjomuljono et al., 2008 ▶) |