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The effect of (A) Acanthus syriacus(AC),(B) FKCA isolated fraction (FKCA), and (C) kromeic acid (KRA) against hyperalgesia on the hot-plate latency in alloxan-treated mice with tramadol (TRA 10mg/kg) as a positive control. “NORM” designates normal non-diabetic mice. "*" shows significant differences atp<0.05, compared tovehicle diabetic-control (DIA+VEH) (n=7).
