Table 3.

In-vivo assessment of the antioxidant activities of Acanthus syriacus (AC), FKCA isolated fraction (FKCA), and kromeic acid (KRA) on serum levels of CAT, reduced GSH, and alterations in TBARS (n=7/group; data presented as Mean ± SEM).

Group	Dose (mg/kg)	Catalase level (kU/I)		GSH (µg/mg)		TBARS Level (nM/100g)
		Predose	8 weeks	Predose	8 weeks	Predose	8 weeks
Normal control	__	32.03±1.40	31.05±1.58	60.30±1.09	60.70±1.08	0.87±0.01	0.84±0.01
Vehicle control	__	22.16±1.00	16.70±1.13	55.53±1.60	39.50±1.50	0.98±0.02	5.30±0.01
MTF a	25	21.93±1.13	22.98±1.18	55.10±1.40	53.90±1.30	1.02±0.01	1.35±0.02
AS a	50	22.54±1.03	38.87±1.25 *	55.43±1.50	74.07±1.00 *	0.91±0.01	0.41±0.01*
AS a	100	22.88±1.21	41.85±1.30 *	54.56±1.40	74.52±1.10 *	0.93±0.02	0.42±0.02 *
AS a	150	22.74±2.25	42.97±1.37 *	56.48±1.10	77.16±1.20 *	0.90±0.02	0.39±0.04 *
FKCA a	5	23.10±1.46	38.10±1.05 *	56.39±1.40	73.01±1.50 *	0.90±0.01	0.42±0.02 *
FKCA a	10	22.10±1.05	40.95±1.60 *	57.96±1.10	73.60±1.10 *	0.94±0.02	0.44±0.02 *
FKCA a	20	23.41±1.60	43.05±1.51 *	57.44±1.20	78.30±1.20 *	0.89±0.03	0.38±0.01 *
KRA a	5	22.29±1.38	30.11±1.35 *	56.04±1.10	63.02±1.10 *	1.06±0.01	0.56±0.01 *
KRA a	10	22.17±1.03	32.32±1.04 *	57.18±1.30	65.00±1.00 *	0.95±0.02	0.53±0.01 *
KRA a	20	22.70±1.68	33.60±1.05 *	55.61±1.60	65.20±1.40 *	0.90±0.01	0.50±0.02 *

SEM.: mean standard error

^* p<0.05 indicates significant differences from the vehicle control animals.

^aCompared to vehicle control.