Representative pretreatment magnetic resonance images of head and neck cancer patient (52 years, male). (A) T2-weighted image, (B) apparent diffusion coefficient ×10−3 (mm2/s) map overlaid on diffusion-weighted (b = 0 s/mm2) images generated using 10 b-values (0, 20, 50, 80, 200, 300, 500, 800, 1500, and 2000 s/mm2), (C) Ktrans (min−1) map overlaid on pre-contrast T1-weighted image. (Images compliments of Amita Shukla-Dave, Memorial Sloan Kettering Cancer Center).