Table 3.
Analysis of 14-day mortality with unadjusted and adjusted cox proportional hazards regression model
| Deaths (%) | Survivors (%) | Unadjusted | Adjusted | |||
|---|---|---|---|---|---|---|
| n=60 | n=508 | Mortality rate ratio (95% CI) | P-value | Mortality rate ratio (95% CI) | P-value(P<0.05 in bold) | |
| Age [median (25–75 percentiles)] | 74 (66–84) | 71 (61–84) | 1.01 (0.99–1.03) | 0.26 | ||
| Gender (female) | 29 (48.3) | 289 (56.9) | 0.71 (0.41–1.21) | 0.22 | ||
| Acquisition (n=503) | ||||||
| Community-acquired | 21 (39.6) | 290 (64.4) | 1.00 | 1.00 | ||
| Health care related | 20 (37.7) | 90 (20.0) | 3.07 (1.59–5.92) | <0.01 | 3.39 (1.77–6.49) | <0.01 |
| Hospital-acquired | 12 (22.6) | 70 (15.6) | 2.37 (1.11–5.04) | 0.03 | 2.17 (1.02–4.62) | <0.05 |
| Charlson Comorbidity Index | ||||||
| Low | 11 (18.3) | 146 (28.7) | 1.00 | 1.00 | ||
| Medium | 21 (35.0) | 186 (36.6) | 1.50 (0.70–3.21) | 0.30 | 1.47 (0.65–3.32) | 0.35 |
| High | 28 (46.7) | 176 (34.6) | 2.11 (1.02–4.39) | <0.05 | 1.93 (1.05–3.53) | 0.06 |
| Intensive care unit | 3 (5.0) | 3 (0.6) | 8.87 (1.75–44.93) | 0.02 | 20.45 (5.31–78.82) | <0.01 |
| Intervention hospital | 14 (23.3) | 161 (31.7) | 0.66 (0.35–1.23) | 0.24 | 0.60 (0.32–1.59) | 0.15 |
| Polymicrobial bacteraemia (n=503) | 2 (3.3) | 14 (2.8) | 1.05 (0.24–4.72) | 1.00 | 1.75 (0.50–6.05) | 0.35 |
| Resistant strain | 17 (28.3) | 94 (18.5) | 1.31 (0.49–3.49) | 0.58 | ||
| Combination with gentamicin | 8 (13.3) | 75 (14.8) | 0.88 (0.41–1.95) | 1.00 | ||
| Combination with ciprofloxacin | 25 (41.7) | 150 (29.5) | 1.71 (0.99–2.95) | 0.08 | 2.14 (0.98–4.68) | 0.04 |
| Treatment with cefuroxime | 45 (75.0) | 332 (65.4) | 1.59 (0.86–2.93) | 0.15 | 3.95 (1.12–13.90) | 0.02 |
Note: P<0.05 shown in bold.