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SpyCEP cleavage of CXCL8 ablates binding to heparin. Graph shows the relative abilities of H292- and H575-treated CXCL8 in binding to heparin Sepharose beads. Error bars represent the mean ± SEM (n = 6). Statistical significance between CXCL8 treatments was determined by two-way ANOVA with Sidak posttest. *p < 0.05, ***p < 0.001.
