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. 2019 May 20;2019(5):CD012855. doi: 10.1002/14651858.CD012855.pub2

Comparison 4. Combined psychological and pharmacological continuation and maintenance therapies versus pharmacological continuation and maintenance therapies alone.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Relapse/recurrence 1 238 Risk Ratio (M‐H, Random, 95% CI) 1.23 [0.44, 3.44]
2 Dropout due to any reason 2 280 Risk Ratio (M‐H, Random, 95% CI) 1.43 [0.90, 2.29]
3 Depression severity 1 39 Mean Difference (IV, Random, 95% CI) 2.8 [0.38, 5.22]
4 Depression severity – follow‐up 1 39 Mean Difference (IV, Random, 95% CI) 0.90 [‐3.26, 5.06]
5 Health‐related quality of life 1 35 Mean Difference (IV, Random, 95% CI) ‐0.5 [‐1.63, 0.63]
6 Health‐related quality of life – follow‐up 1 33 Mean Difference (IV, Random, 95% CI) 0.60 [‐0.56, 1.76]