Table 2.
Summary of observations after subcutaneous injection of sodium pentobarbital into hindpaw
| Sodium pentobarbital (mg/mL) | No. of responders | Time (s) until first lick | No. of licks per responder | Paw colorb |
| 0 (n = 20) | 8 | 271.9 ± 280.7 | 3.0 ± 3.0 | 2.2 ± 0.4 |
| 5 (n = 22) | 14 | 291.9 ± 176.9 | 1.8 ± 1.1 | 2.4 ± 0.8 |
| 50 (n = 22) | 16a | 254.9 ± 117.2 | 1.4 ± 0.8 | 4.0 ± 0.0c |
| 390 (n = 20) | 13 | 326.3 ± 292.6 | 1.5 ± 1.0 | 5.0 ± 0.2d |
Data are given as mean ± 1 SD where appropriate.
a
Significant (P = 0.0170) difference in the number of responders within 10 min between 50-mg/mL and saline groups
b
Significant (P < 0.0001) effect of treatment on paw color at 10 min after injection
c
Significant (P < 0.0001) difference in paw color at 10 min after injection between 50-mg/mL and saline groups
d
Significant (P < 0.0001) difference paw color at 10 min after injection between 390-mg/mL and saline groups