Table 3.

Creatinine and urine specific gravity in the pilot animal after 1.5 mg/kg SRM

Time (h)	Creatinine (mg/dL; reference interval, 0.5–1.0)	Urine specific gravity
0	1.1	1.005
24	3.0	1.008
48	3.7	1.009
120	1.5	1.011

Note the evidence of acute renal azotemia beginning at 24 h after administration, worsening at 48 h, and showing improvement of signs at 120 h.