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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: Acta Biomater. 2019 Mar 14;89:95–103. doi: 10.1016/j.actbio.2019.03.023

Figure 1.

Figure 1

Anti-PEG IgG antibodies trap 200 nm PEG-coated nanoparticles in MG. (A) Representative traces in MG with 10 µg/mL control IgG or anti-PEG IgG (5 or 10 µg/mL). (B) Distribution of effective diffusivities of nanoparticles under different conditions. (C) Ensemble averaged mean squared displacements (<MSD>) over time. **** p < 0.0001 compared to Control IgG by two-way RM ANOVA with post hoc Šidák test. (D) Average ensemble effective diffusivities (<Deff>) at a time scale of 1 s. (E) Fraction of mobile nanoparticles. For (D) & (E) **** p < 0.0001 compared to Control IgG by one-way ANOVA with post hoc Šidák test. Error bars represent SEM.