Figure 6.

Influence of temperature at 39–40°С and 42–43°С on spectrin matrix nanostructure. (a, e) AFM 3D images of RBC morphology, 38 × 38 μm² and 60 × 60 μm². (b, f) AFM 2D images of the spectrin matrix, 12 × 12 μm². (c, g) AFM 2D images of a fragment of the spectrin matrix nanostructure, 2000 × 2000 nm². (d) Height profile along the lines indicated in (c, h, g). Red arrows correspond to dashed lines on the profile. The curly bracket unites possible variants of RBC ghosts and spectrin matrix at 39–40°С. The vertical arrow shows a ghost RBC variant and the spectrin matrix at 42–43°С. Ensemble 1 of RBC ghosts corresponds to (b–d). Ensemble 2 of RBC ghosts corresponds to (f–h).