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. 2019 May 20;7:80. doi: 10.1186/s40478-019-0733-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Representative immunohistochemistry of microglia and astrocytes in M83^+/− mice neonatally injected at P0 with PBS, WT human αS fibrils, A53T human αS fibrils or MSA brain lysates. M83^+/− mice were injected at P0 as described in “Material and Methods” and aged. Images showing microgliosis with an anti-CD11B antibody and astrogliosis with an anti-GFAP antibody in the pons of mice with induced αS pathology. Scale bar = 50 μm