Figure 4.
Effect of metyrapone on brain norepinephrine turnover in male rats. Two hours after saline or metyrapone administration animals were euthanized for measurement of norepinephrine turnover in the hippocampus (A), amygdala (B), hypothalamus (C), and medial prefrontal cortex (D). A significant main effect of metyrapone treatment was observed in the hypothalamus and medial prefrontal cortex. * represent significant (p < 0.05) main effect of metyrapone treatment compared to saline-injected controls. Values represent group means of norepinephrine turnover. Symbols and bars represent group mean ± SEM.