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. Author manuscript; available in PMC: 2019 May 20.
Published in final edited form as: Anal Chem. 2017 Dec 5;90(1):266–282. doi: 10.1021/acs.analchem.7b04380

Figure 5.

Figure 5.

SAMDI mass spectrometry assays. (A) Laser irradiation of the monolayer releases alkanethiolates (or corresponding disulfides) and provides the mass of peptide-alkanethiolate conjugates.123 Readapted with permission from Mrksich, M. ACS Nano 2008, 2, 7–18 (ref 123). Copyright 2008 American Chemical Society. (B) Example of SAMDI MS detection of acetyltransferase activity.129 Readapted with permission from Kornacki, J. R.; Stuparu, A. D.; Mrksich, M. ACS Chemical Biology 2015, 10, 157–164 (ref 129). Copyright 2015 American Chemical Society.