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The silencing of TLR9 inhibits invasion, whereas Helicobacter pylori (H. pylori) DNA promotes cell invasion in MKN45 cells. MKN45 cells were transfected with the scrambled miRNA or indicated miRNA and cocultured with H. pylori DNA, respectively. **P < 0.01, compared with the blank group; ##P < 0.01, compared with the NC + DNA group
