Table 3. Brain Regions Consistently Engaged During Affective Compared With Neutral Stimulus Conditions in WM Tasks.
| Region | L/R | Cluster size (voxels) | Subcluster size (voxels) | Maximum | x/y/z |
|---|---|---|---|---|---|
| Note. Table 3 reports brain regions that were significantly more frequently activated in response to one condition compared with another. Peak activations for each (sub)cluster are reported as well as the maximum statistic, which reflects the analysis of the distribution of maximum values corrected for multiple comparisons at a FWER of .05 (Salimi-Khorshidi, Smith, Keltner, Wager, and Nichols, 2009; Wager, Lindquist, and Kaplan, 2007). dl = dorsolateral; vl = ventrolateral; PFC = prefrontal cortex; OFC = orbitofrontal cortex; L = left; R = right; Maximum = maximum of the z-field. The negative > neutral comparison was based on 211 coordinates from 24 contrasts; the neutral > negative comparison was based on 144 coordinates from 20 contrasts. | |||||
| Negative > Neutral Stimuli | |||||
| vlPFC/OFC | L | 228 | .31 | −39/33/−6 | |
| 71 | −39/36/3 | ||||
| Amygdala | L | 338 | .35 | −27/−3/−18 | |
| 103 | −24/−12/−18 | ||||
| 80 | −18/0/−18 | ||||
| 46 | −21/−6/−6 | ||||
| Temporal lobe (including amygdalo-hippocampal complex) | R | 419 | .50 | 21/−6/−18 | |
| 48 | 36/0/−24 | ||||
| 51 | 39/−3/−15 | ||||
| Temporo-occipital lobe (including fusiform gyrus) | L | 648 | .29 | −39/−57/−12 | |
| 192 | −42/−78/0 | ||||
| 93 | −45/−75/12 | ||||
| 110 | −36/−51/−21 | ||||
| 36 | −51/−63/6 | ||||
| 34 | −48/−51/3 | ||||
| Temporo-occipital lobe (including fusiform gyrus) | R | 512 | .33 | 42/−54/−18 | |
| 110 | 39/−75/−12 | ||||
| 87 | 42/−45/−12 | ||||
| 70 | 42/−72/0 | ||||
| 45 | 48/−69/−12 | ||||
| 33 | 42/−54/−6 | ||||
| 60 | 54/−69/6 | ||||
| Neutral > Negative stimuli | |||||
| dlPFC | R | 505 | .49 | 36/42/30 | |
| 180 | 36/33/33 | ||||
| 34 | 27/51/12 | ||||
| 51 | 33/54/18 | ||||
| 44 | 33/39/42 | ||||
| 21 | 27/30/51 | ||||