Table 2.

AUC for All M8-Based Simulations (see Fig. 1) and for BUSTED.

	Simulation
Estimation	No Var.	Site Var.	Codon 3-Rate Var.	Codon Gamma Var.
No variation	0.916 100%	0.846 94.4%	0.785 88.8%	0.758 84.5%
Site variation	0.912 99.6%	0.897 100%	0.812 91.9%	0.806 89.7%
Codon 3-rate variation	0.900 98.2%	0.862 96.1%	0.884 100%	0.880 98.0%
Codon gamma variation	0.912 99.6%	0.875 97.6%	0.867 98.1%	0.898 100%
BUSTED	0.865 94.5%	0.819 91.3%	0.749 80.2%	0.749 84.8%

note.—Second number computed as proportion of maximum AUC for a particular simulation.