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. 2019 May 15;14:3557–3569. doi: 10.2147/IJN.S198511

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© 2019 Chen et al.

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Figure S2 — (A) siRNA release profiles of siRNA-Dox-SiO₂ nanocarrier in PBS at different time points (1, 12, 24, 48, 72 and 96 hrs). (B) Agarose gel electrophoretic analysis to evaluate the siRNA release at different time points. Lane 1: 1 hr; Lane 2: 12 hrs; Lane 3: 24 hrs; Lane 4: 48 hrs; 5: 72 hrs; Lane 6: 96 hrs; 7: free siRNA (equivalent to the total loaded siRNA in siRNA-Dox-SiO₂ nanocarriers); 8: DNA ladder (50 bp).

Abbreviations: siRNA, small interfering RNA; Dox, doxorubicin; SiO₂, silica; PBS, phosphate-buffered saline; DNA, deoxyribonucleic acid.