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. Author manuscript; available in PMC: 2020 Apr 11.
Published in final edited form as: J Med Chem. 2019 Mar 21;62(7):3677–3695. doi: 10.1021/acs.jmedchem.9b00164

Figure 4.

Figure 4

Concentration−inhibition curves of selected compounds at membrane preparations of the human triple-negative breast cancer cell line MDA-MB-231 which natively expresses CD73. Km: 14.8 μM; AMP concentration: 5 μM; Data points are from three separate experiments performed in duplicates. For Ki values see Table 5.