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Inhibitory potency at rat ecto-5′-nucleotidase of 3-deazauridine-derived (10), (S)-methanocarba-based (11) nucleotides and ethyl ester 12.
 | |
|---|---|
| Compd. | Ki (nM) (% inhibition at indicated concentration) rat CD73 |
| 10 | > 1000 (19%) |
| 11 | > 1000 (12%) |
| 12 | > 1000 (10%) |
