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. 2019 Apr 2;10(1):260–276. doi: 10.1080/21505594.2019.1596507

Figure 2.

Figure 2.

The relative antibiotic sensitivity (SRel) of wild-type E. coli strains (No. 1, No. 5, No. 6, No. 16, and No. 84) and their derivatives isolated during the treatment with a subinhibitory concentration of antibiotics (ciprofloxacin, amoxicillin, gentamycin, and tobramycin). The sensitivity was measured for all studied antibiotics (CIP – ciprofloxacin, NOR – norfloxacin, OFX – ofloxacin, AML – amoxicillin, AMC – amoxicillin/clavulanate, PRL – piperacillin, CAZ – ceftazidime, FOX – cefoxitin, CTX – cefotaxime, IMI – imipenem, GN – gentamycin, TN – tobramycin, AK – amikacin, NET – netilmicin, NI – nitrofurantoin, W – trimethoprim, SXT – trimethoprim/sulfamethoxazole). The results (SRel) represent the ratio between the medium value of diameter zone of inhibited growth of E. coli strains (wild type or derivatives) and the limit value of the sensitivity diameter zone according to the clinical breakpoint tables from EUCAST 2018. The value 1 on the Y axis means the limit value of the diameter zone of inhibited bacterial growth corresponding to sensitivity according to the clinical breakpoint tables of EUCAST 2018. The statistically significant (p < 0.05)* difference between the sensitivity to individual antibiotics was determined using a two-tailed, paired T-test (GraphPad Prism, version 6; San Diego, CA, USA), ns – not statistically significant.