Table 3.

Predictive Features for Complicated CDI at Diagnosis and 2 Days After

Day of Diagnosis		2 Days After Diagnosis
Rank	Associated With Higher Estimated Risk	Rank	Associated With Higher Estimated Risk
1	Obtaining adult blood culture	1	High respiratory rate (>20 breaths/min)
2	High respiratory rate (>20 breaths/min)	2	Low respiratory rate (<12 breaths/min)
3	Low blood CO2 (<23 mmol/L; Q 1/5)	3	Low systolic BP (<90 mmHg)
Rank	Associated With Lower Estimated Risk	Rank	Associated With Lower Estimated Risk
1	Normal respiratory rate (12–20 breaths/min)	1	Missing PTT measurement
2	Low RDW (<14.6%; Q 1/5)	2	Normal respiratory rate (12–20 breaths/min)
3	Age (<41 years old; Q 1/5)	3	Missing phosphorous level measurement

Please see Supplementary Table 2 for the model coefficients associated with these features.

Abbreviations: BP, blood pressure; CDI, Clostridium difficile infection; PTT, partial thromboplastin time; RDW, red cell distribution width.