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. 2019 May 15;12:3661–3670. doi: 10.2147/OTT.S200901

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© 2019 Wu et al.

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IMP3 affects the survival of nude mice and EMT biomarkers in U87 cells. (A) The survival rates of nude mice containing U87 cells with IMP3 over-expression or IMP3 silencing were determined as follows: 100%×(number of survivors)/(number of challenged mice). (B) Western blot analysis was used to assess the levels of E-cadherin, N-cadherin, vimentin, snail, slug and MMP9 in U87 cells with over-expression of IMP3. (C) Western blot analysis was used to assess the levels of E-cadherin, N-cadherin, vimentin, snail, slug and MMP9 in U87 cells with IMP3 siRNAs. Data are presented as Mean ± SD of at least three independent experiments or 3 cases of representative samples. *P<0.01 vs their respective controls.