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. 2019 Apr 1;294(20):8171–8183. doi: 10.1074/jbc.RA118.005009

Table 5.

IC50 of DHA and CQ in combination with B02

Strain Combination of drugs IC50 (mean ± S.D.) Potentiation factor
nm
3D7 DHA (alone) 59.7 ± 3.27 1
DHA (B02)a 3.89 ± 2.04 15.34
CQ (alone) 26.4 ± 1.98 1
CQ (B02)a 3.17 ± 0.47 8.33
Dd2 DHA (alone) 64.8 ± 3.56 1
DHA (B02)b 14.1 ± 3.06 4.6
CQ (alone) 63.5 ± 2.33 1
CQ (B02)b 9.8 ± 0.71 6.48

a IC50 concentration of B02 in 3D7 strain was used.

b IC50 concentration of B02 in Dd2 strain was used.