Table 5.
Strain | Combination of drugs | IC50 (mean ± S.D.) | Potentiation factor |
---|---|---|---|
nm | |||
3D7 | DHA (alone) | 59.7 ± 3.27 | 1 |
DHA (B02)a | 3.89 ± 2.04 | 15.34 | |
CQ (alone) | 26.4 ± 1.98 | 1 | |
CQ (B02)a | 3.17 ± 0.47 | 8.33 | |
Dd2 | DHA (alone) | 64.8 ± 3.56 | 1 |
DHA (B02)b | 14.1 ± 3.06 | 4.6 | |
CQ (alone) | 63.5 ± 2.33 | 1 | |
CQ (B02)b | 9.8 ± 0.71 | 6.48 |
a IC50 concentration of B02 in 3D7 strain was used.
b IC50 concentration of B02 in Dd2 strain was used.