Collagen I, fibronectin, IL-1, IL-6 expression in the high glucose, Ad-EGFP, Ad-PRR, and Ad-PRR + PD98059 groups in vitro in cardiac fibroblasts.
A, collagen I mRNA expression; B, ELISA of collagen I protein expression; C, fibronectin mRNA expression; D, ELISA of fibronectin protein expression; E, IL-1 mRNA expression; F, ELISA of IL-1 protein expression; G, IL-6 mRNA expression; H, ELISA of IL-6 protein expression. *, p < 0.05 compared with the high glucose and Ad-EGFP groups; #, p < 0.05 compared with Ad-PRR group.