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. 2019 Mar 29;294(20):8015–8022. doi: 10.1074/jbc.RA119.007928

Figure 1.

Figure 1.

Conformational differences between apo 3A5 (yellow) and apo 3A4 (magenta; A and B), apo 3A5 and the 3A5 ritonavir complex (green; C and D), and apo 3A4 and the 3A4 ritonavir complex (cyan; E and F). Ritonavir is depicted as spheres. Heme is depicted as a stick model with an iron sphere. Heteroatom colors are nitrogen (blue), oxygen (red), iron (orange), and sulfur (yellow). Distances (dashed lines) are reported in angstroms.