Fig 7. Short term UV-induced epidermal thickening in wild-type and β2-adrenergic receptor knockout mice.

Hairless mice were exposed to 200 mJ/cm² UV on day 1 and subsequently exposed to radiation every other day. On opposing days bi-fold epidermal thickness was measured with calipers, then the mice were treated with vehicle, 5 μM 4-OHC, or 5 μM carvedilol. Closed symbols represent wild type and open symbols knockout. Statistical analysis was conducted by a 3-Way RM-ANOVA and a Tukey-Kramer post hoc test. For clarity, statistical differences are noted in the text. Data represented as mean ± SD; n = 3, except for 4-OHC which had two mice in each group.