Table 2.
Univariate and multivariate cox regression analyses circ-BIRC6 for OS of patients in the cohort.
| Variables | Univariate analysis |
Multivariate analysis |
||
|---|---|---|---|---|
| HR (95%CI) | P values | HR (95%CI) | P values | |
| Circ-BIRC6 (High vs. low) | 2.820(1.225–5.026) | 0.005 | 2.343(1.088–5.044) | 0.030 |
| Age (>60 vs.≤60 y) | 1.001(0.974–1.029) | 0.930 | - | - |
| Gender (M vs. F) | 1.393(0.675–2.877) | 0.370 | - | - |
| HBsAg (positive vs. negative) | 1.526(0.757–3.078) | 0.237 | - | - |
| AFP (>20ng/ml vs.<20ng/ml) | 1.754(0.886–3.473) | 0.107 | - | - |
| Vascular invasion (positive vs. negative) | 2.727(1.324–5.615) | 0.006 | 2.530(1.100–5.814) | 0.029 |
| Tumor size (>5cm vs.≥5cm) | 2.025(1.016–4.036) | 0.045 | 1.188(0.532–2.653) | 0.675 |
| Edmonson grade (IV+III vs. I+ II) | 2.207(1.110–4.389) | 0.024 | 1.059(0.446–2.519) | 0.896 |
| TNM stage (III+IV vs. I+ II) | 3.098(1.543–6.217) | 0.001 | 2.879(1.258–6.590) | 0.012 |