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. 2018 Aug 29;13(1):41–49. doi: 10.1080/19336918.2018.1506653

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — The expression of HDAC4, MEG3, miR-125a-5p and IRF1 in VSMCs induced by PDGF-BB. VSMCs were isolated from the thoracic aortas of health SD rats by using enzymatic dissociation, then cultured in DMEM medium containing 10% FBS. In the experiment, VSMCs were divided into control group and PDGF-BB group (cells were treated with 20 ng/ml PDGF-BB for 24 h). (a) The expression of MEG3 and miR-125a-5p was detected using qRT-PCR. (b) The protein expression of HDAC4 and IRF1 was measured by western blot. *P < 0.05, vs control group.