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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Thromb Haemost. 2018 Apr 25;118(6):1048–1057. doi: 10.1055/s-0038-1645855

Fig. 2.

Fig. 2

Ultrasonography and histology to validate the experimental design principles of the IVC recurrent model. Ultrasonography was performed in all animals prior to second insult (A) and post-second insult (B and C); (A) Ultrasound showing IVC patency to host the secondary thrombi; (B) Ultrasonography performed after the second insult and histology showing the primary thrombus incorporated to the vein wall co-existing with the new (EIM) thrombus and its lumen within the IVC. (C) Ultrasonography post-second insult and histology showing the primary thrombus incorporated to the vein wall and the new thrombus totally occluded in the IVC secondary to the ligation model. White arrow: lumen; black arrows: primary thrombus incorporated to the vein wall. Abbreviations: EIM, electrolytic IVC model; IVC, inferior vena cava.