Table 1:
Characteristic | Control | Maternal Obesity | p-value |
---|---|---|---|
Dam weight at breeding (g)* | 20.60 ± 0.58 | 31.83 ± 0.94 | 0.02 |
Dam weight at sacrifice (g) | 36.38 ± 1.13 | 42.97 ± 1.80 | 0.03 |
Litter size | 8.8 ± 1.2 | 6.25 ± 1.49 | 0.24 |
Fetal weight (g) | |||
Male | 0.96 ± 0.03 | 0.97 ± 0.03 | 0.93 |
Female | 0.86 ± 0.04 | 0.91 ± 0.02 | 0.67 |
Both sexes combined | 0.90 ± 0. 03 | 0.93 ± 0.02 | 0.57 |
Placental weight (g) | |||
Male | 0.12 ± 0.01 | 0.11 ± 0.01 | 0.59 |
Female | 0.11 ± 0.01 | 0.10 ± 0.01 | 0.19 |
Both sexes combined | 0.12 ± 0. 01 | 0. 10 ± 0. 01 | 0.13 |
CD11b+ cells isolated from brain | |||
Male | 3.85 × 105± 0.63 | 7.42 × 105 ± 1.14 | 0.02 |
Female | 4.65 × 105 ± 0.50 | 7.75 × l05 ± 0.81 | 0.003 |
Both sexes combined | 4.25 × 105 ± 0.40 | 7.60 × 105 ± 0.66 | <0.001 |
CD11b+ cells isolated from placenta | |||
Male | 7.02 × 105 ± 1.54 | 8.32 × 105 ± 1.37 | 0.47 |
Female | 7.21 × 105 ± 1.86 | 6.23 × 105 ± 0.76 | 0.99 |
Both sexes combined | 7.171× 105 ± 1.16 | 7.27 × 105 ± 0.80 | 0.59 |
CD11b− cells isolated from brain | |||
Male | 9.13 × 106 ± 2.12 | 10.33 × 106 ± 1.30 | 0.35 |
Female | 10.03 × 106 ± 1.56 | 14.52 × 106 ± 2.89 | 0.24 |
Both sexes combined | 9.57 × 106 ± 1.28 | 12.56 × 106 ± 1.69 | 0.16 |
CD11b− cells isolated from placenta | |||
Male | 4.42 × 106 ± 0.77 | 4.22 × 106 ± 0.36 | 0.91 |
Female | 3.12 × 106 ± 0.60 | 4.90 × 106 ± 0.28 | 0.03 |
Combined | 3.77 × 106 ± 0.50 | 4.58 × 106 ± 0.24 | 0.09 |
Data are expressed as mean ± SEM unless otherwise indicated