Fig. 5.

SA inhibits inflammation and demyelination in the CNS of EAE mice. A, B Representative images of fluoromyelin (A) and Luxol fast blue staining (B) of spinal cord sections in EAE mice in the SA and vehicle groups at 25 dpi. C Representative images of H&E staining showing infiltrating cells in spinal cord sections from EAE mice in the SA and vehicle groups at 25 dpi. D, E Quantitative analysis of the demyelination area and number of infiltrating cells as in B and C. Data are shown as mean ± SEM, n = 5/group in each experiment, *P < 0.05, **P < 0.01, ***P < 0.001, one-way ANOVA with Tukey’s post hoc test. Scale bars, 100 μm.