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. 2019 May 20;9:7599. doi: 10.1038/s41598-019-44078-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparisons in functional and anatomical courses between eyes with and without early remission of DME at 6 months following PRN IVR injections. The course of the logMAR VA (a) and its improvement (b) in eyes with and without early remission of DME under PRN IVR injections following three monthly loading doses. The course of the CSF thickness (c) and its changes (d). (e) The percentage of eyes that received IVR injection at individual time points. Black = eyes with early remission of DME at 6 months. Gray = eyes without early remission.