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Molecular mechanisms underlying the regulation of insulin sensitivity by zinc-α2-glycoprotein (ZAG). Descriptions of molecules and arrows in different colors are as in Fig. 1. GLUT4, glucose transporter 4; IRS, insulin receptor substrate; PP2A, protein phosphatase 2A; PPARγ, peroxisome proliferator-activated receptor γ; SGLT2, sodium-dependent glucose transporter 2.
