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Serum contents of D-dimer during acute phase of oral T. cruzi infection.
| Group | Mice with D-dimer>0 ng/mL |
|---|---|
| NI | 0/6 |
| 7 dpi | 0/5 |
| 14 dpi | 3/6 |
| 21 dpi | 2/6 |
Male BALB/c mice were infected with 5 × 104 insect-derived metacyclic forms of T. cruzi within the oral cavity. NI or OI sera were obtained by cardiac puncture and used to measure levels of D-dimer by ELISA. The mean and SEM of animals with detectable levels of D-dimer were 25.7 ± 7.59 and 45.1 ± 11.0 for 14 and 21 dpi, respectively.
