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. 2019 May 14;6:59. doi: 10.3389/fcvm.2019.00059

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Copyright © 2019 Dal Ferro, De Paris, Collia, Stolfo, Caiffa, Barbati, Korcova, Pinamonti, Zovatto, Zecchin, Sinagra and Pedrizzetti.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Receiver Operating Characteristic Analysis (ROC) on the all grade Responder Status (R/RS, vs. NR/NegR) at midterm follow, for the hemodynamic force ratio: (A) RMSx/RMSz measured PRE implant, (B) RMSx/RMSz measured POST implant, and (C) early variation δ(RMSx/RMSz) from PRE implant to POST implant. The presence of poor alignment of forces before implant has a mild predictive value for the responder status (A); this does not apply for the value measured after implant (B). Moreover, the improvement of alignment induced by biventricular pacing shows the best predictive value of the eventual responder status at follow up.