Table 1.

Clinical correlation analysis with viral and immunologic parameters.

			CD4/CD8
				Adjusted P
	r	(95% CI)	P	BH	Bonferroni
SINGLE PARAMETER
Neut	0.66	(0.20 – 0.88)	0.05	0.12	0.45
ADCC (N-U-)	0.40	(0.13 – 0.62)	0.22	0.28	0.90
ADCC (WT)	−0.01	(−0.02 – 0)	0.97	0.97	1.00
cell stain (N-U-)	0.64	(0.23 – 0.86)	0.04	0.07	0.34
cell stain (WT)	0.70	(0.26 – 0.90)	0.02	0.05	0.24
IgA (Env)	−0.23	(−0.38 – −0.07)	0.50	0.54	1.00
IgG (Env)	0.72	(0.27 – 0.91)	0.02	0.05	0.21
IgA/IgG (Env)	−0.37	(−0.58 – −0.12)	0.26	0.30	0.90
V1V2/CaseA2 mut3	0.62	(0.22 – 0.84)	0.05	0.07	0.34
K169	0.70	(0.17 – 0.92)	0.04	0.07	0.34
PVL	−0.67	(−0.88 – −0.24)	0.03	0.06	0.27
MULTIPLE PARAMETER
IgG (Env) & cell stain (N-U-)	0.72	(0.27 – 0.91)	<0.001	<0.001	<0.001
IgG (Env) & cell stain (WT)	0.75	(0.29 – 0.93)	<0.001	<0.001	<0.001
V1V2/CaseA2 mut3 & K169	0.71	(0.27 – 0.91)	<0.001	<0.001	0.001
ADCC (N-U-) & IgA/IgG (Env)	0.45	(0.15 – 0.68)	0.02	0.05	0.24
ADCC (WT) & IgA/IgG (Env)	0.40	(0.13 – 0.62)	0.04	0.07	0.34

Table of linear and multivariate correlation analyses (Spearman rank) of various viral, immunologic, and clinical parameters with CD4/CD8 ratios.

Correlation coefficients r, 95% confidence intervals (CI), significance P and multiple-comparisons-adjusted P-values (Benjamini-Hochberg (BH) and Bonferroni method) are displayed; statistically significant results (P < 0.05) are highlighted in bold. Env, Env-specific; Neut, Neutralization breadth-potency score; N-U-, Nef- and Vpu-deficient virus infection; PVL, plasma viral load; WT, wild-type infection.