Table 3.
Dosage and blood level results for the patients
| Gentamicin N (%) |
Amikacin N (%) |
|
| Dosage | ||
| 240 mg/day | 38 (58.5) | n/a |
| 160 mg/day | 10 (15.4 | n/a |
| 400 mg/day | 7 (10.8) | n/a |
| 180 mg/day | 5 (7.7) | n/a |
| 320 mg/day | 2 (3.1) | n/a |
| 80 mg 8-hourly | 2 (3.1) | n/a |
| 480 mg/day | 4 (1.5) | n/a |
| 1000 mg/day | n/a | 30 (78.95) |
| 500 mg 12-hourly | n/a | 5 (13.16) |
| 750 mg/day | n/a | 2 (5.26) |
| 1000 mg 12-hourly | n/a | 1 (2.63) |
| TDM results | ||
| <1 mg/L | 13 (20.00) | n/a |
| >1 mg/L | 6 (9.23) | n/a |
| <5 mg/L | n/a | 19 (50.00) |
| >5 mg/L | n/a | 3 (7.89) |
| No TDM done | 46 (70.77) | 16 (42.11) |
| TDM for eGFR< 60 mL/min/1.73m2 | ||
| TDM done | 2 (100) | 1 (100) |
| TDM not done | 0 | 1 |
| TDM for eGFR> 60 mL/min/1.73m2 | ||
| TDM done | 17 (29.31) | 21 (56.76) |
| TDM not done | 41 (70.69) | 16 (43.24) |
| TDM done where eGFR not tested | ||
| TDM done | 0 | 0 |
| TDM not done | 5 (100) | 0 |
| Sampling times | ||
| 0–1 hour before next dose | 1 (5.26) | 5 (22.73) |
| 1–2 hours before next dose | 6 (31.58) | 5 (22.73) |
| > 2 hours before next dose | 12 (63.16) | 12 (54.54) |
| TDM = Therapeutic drug monitoring n/a = Dosage range not applicable to specific drug | ||