Fig. 5.
Upregulated tissue repair-related genes by MSC-dressing therapy. Heart samples after transplantation of 4 × 106 rat amnion-derived MSCs (either by MSC-dressing technique or IM injection; DR-4m and IM-4m groups, respectively) in a rat post-MI ischemic heart failure model were collected and assessed for myocardial expression of reparative genes by Real time RT-PCR at day 3 (a) and day 28 (b) post-treatment. The DR-0 group received transplantation of fibrin sealant film only, while the Sham group received no treatment. Expression in the Sham group was arbitrarily defined as 1.0. n = 5 in each group, *p < 0.05 vs. Sham and DR-0 groups,†p < 0.05 vs. IM-4m group. One-way ANOVA.