Table 2.
Baseline characteristics and 90 day clinical outcomes according to infection category.
| Number of infections | Any infection 3081 | Pneumonia 958 | Tracheobronchitis 170 | Urogenital infection 1132 | Other infection 330 | Uncertain infection 491 |
|---|---|---|---|---|---|---|
| Number of patients | 2708 | 958 | 170 | 1132 | 330 | 490 |
| Median (IQR) age (y) | 74 (65 to 80) | 74 (66 to 80) | 72 (65 to 78) | 74 (66 to 80) | 73 (64 to 80) | 73 (65 to 79) |
| Female sex, n (%) | 1372 (51%) | 387 (40%) | 67 (39%) | 727 (64%) | 140 (42%) | 225 (46%) |
| Median (IQR) NIHSS | 15 (11 to 19) | 16 (12 to 20) | 13 (9 to 17) | 14 (11 to 18) | 14 (10 to 17) | 16 (12 to 20) |
| Median (IQR) time to first infection (d) | 5 (3 to 9) | 4 (2 to 7) | 3 (2 to 7) | 6 (3 to 14) | 6 (3 to 21) | 4 (2 to 6) |
| IV thrombolysis, n (%) | 795 (26%) | 270 (28%) | 44 (26%) | 282 (25%) | 75 (23%) | 124 (25%) |
| Mean (SD) pre-stroke mRS | 1.2 (0.6) | 1.2 (0.6) | 1.1 (0.3) | 1.3 (0.7) | 1.3 (0.8) | 1.2 (0.5) |
| Median (IQR) glucose concentration (mmol/L) | 6.9 (5.8 to 8.6) | 7.0 (5.9 to 9.0) | 6.9 (5.7 to 9.1) | 6.7 (5.7 to 8.2) | 6.8 (5.8 to 8.4) | 7.2 (6.0 to 8.7) |
| Prior statin, n (%) | 210 (6%) | 43 (4%) | 10 (6%) | 97 (9%) | 32 (10%) | 28 (6%) |
| Vascular risk factors, N (%) | ||||||
| Previous stroke | 558 (19%) | 184 (20%) | 35 (21%) | 197 (18%) | 64 (20%) | 78 (17%) |
| Previous TIA | 258 (9%) | 83 (9%) | 10 (6%) | 96 (9%) | 28 (9%) | 41 (9%) |
| Diabetes mellitus | 685 (22%) | 231 (24%) | 42 (25%) | 218 (19%) | 71 (22%) | 123 (25%) |
| Hypertension | 1994 (66%) | 609 (64%) | 115 (69%) | 731 (66%) | 213 (65%) | 326 (67%) |
| Previous myocardial infarction | 390 (13%) | 142 (15%) | 16 (10%) | 136 (12%) | 46 (14%) | 50 (10%) |
| Atrial fibrillation | 841 (29%) | 302 (33%) | 43 (27%) | 277 (27%) | 78 (26%) | 141 (31%) |
| Smoking status | ||||||
| Non-smoker | 322 (10%) | 94 (10%) | 10 (6%) | 133 (12%) | 37 (11%) | 48 (10%) |
| Smoker | 495 (16%) | 147 (15%) | 19 (11%) | 191 (17%) | 63 (19%) | 75 (15%) |
| 90 day outcomes, median (IQR) | ||||||
| mRS | 4 (3 to 6) | 5 (4 to 6) | 4 (2 to 5) | 4 (2 to 5) | 4 (2 to 6) | 4 (3 to 6) |
| BI | 25 (0 to 80) | 5 (0 to 55) | 55 (0 to 95) | 50 (5 to 85) | 30 (0 to 85) | 10 (0 to 70) |
| NIHSS | 11 (4 to 42) | 17 (7 to 42) | 7 (3 to 42) | 8 (3 to 16) | 11 (3 to 42) | 13 (5 to 42) |
| 90 day case fatality, n (%) | 794 (26%) | 353 (37%) | 39 (23%) | 157 (14%) | 84 (26%) | 161 (33%) |
NIHSS, National Institutes of Health Stroke Scale; mRS, modified Rankin Scale; TIA, transient ischemic attack; BI, Barthel Index.