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. 2019 May 9;9(5):e027655. doi: 10.1136/bmjopen-2018-027655

Table 4.

Rate ratios for developmental vulnerability according to the combination of Apgar scores at 1 and 5 min, singleton term live births, British Columbia, Canada

1 min Apgar 5 min Apgar Total number of children Developmental vulnerability
No. with outcome (%) Rate ratio (95% CI)
Crude Adjusted* P for trend
7 <7 20 9 (45.0) 1.62 (0.99 to 2.65) 1.34 (0.80 to 2.25)
7 7 172 56 (32.6) 1.18 (0.93 to 1.48) 1.18 (0.94 to 1.47)
7 8 1987 629 (31.7) 1.14 (1.02 to 1.28) 1.12 (1.01 to 1.23)
7 9 8700 2637 (30.3) 1.09 (0.99 to 1.20) 1.08 (0.99 to 1.19)
7 10 1140 317 (27.8) 1.00 (reference) 1.00 (reference) 0.024
8 <8 66 17 (25.8) 0.85 (0.56 to 1.28) 0.71 (0.47 to 1.07)
8 8 1337 420 (31.4) 1.03 (0.94 to 1.13) 1.01 (0.92 to 1.10)
8 9 33 255 10 007 (30.1) 0.99 (0.94 to 1.04) 0.97 (0.93 to 1.02)
8 10 4013 1222 (30.5) 1.00 (reference) 1.00 (reference) 0.36
9 <9 140 48 (34.3) 1.17 (0.93 to 1.47) 1.10 (0.88 to 1.38)
9 9 50 976 15 501 (30.4) 1.03 (1.01 to 1.06) 1.03 (1.01 to 1.05)
9 10 28 253 8303 (29.4) 1.00 (reference) 1.00 (reference) 0.009
10 <10 26 13 (50.0) 1.68 (1.14 to 2.47) 1.53 (1.08 to 2.17)
10 10 3057 911 (29.8) 1.00 (reference) 1.00 (reference) 0.016†

*Adjusted for child’s sex (male vs female), child’s age at EDI completion (years), socioeconomic status (first quintile, second quintile, third quintile, fourth quintile vs fifth quintile), child’s first language (others vs English), birth order (2, 3, +4 vs 1), birth weight-for-gestational age (large, small vs appropriate) and gestational age (weeks).

†P value for difference in rates.

EDI, Early Development Instrument.